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 Concern
 Treatment
Pregnancy
Experiences
Treatment
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First Step
Clomiphene Citrate
If testing indicates an ovulatory problem,
hormonal therapy will probably be recommended. Typically, a doctor
will begin ovulation induction with a clomiphene citrate
medication. Clomiphene citrate is prescribed for women with
ovulatory dysfunction whose male partners are fertile.
In a normal cycle, the hypothalamus releases a hormone called
gonadotropin-releasing hormone (GnRH) at the beginning of the
follicular phase. If too little or too much is released, normal
follicle development will not take place and ovulation will not
occur. Clomiphene citrate stimulates the release of GnRH, which in
turn causes the pituitary gland to release more FSH and LH,
stimulating follicular growth in the ovaries.
If clomiphene citrate therapy is ineffective after three to four
cycles, medications containing FSH and LH may be
prescribed.
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